Health-related quality of life in patients with high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study.
Identifieur interne : 001D75 ( Main/Exploration ); précédent : 001D74; suivant : 001D76Health-related quality of life in patients with high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study.
Auteurs : Jaap C. Reijneveld [Pays-Bas] ; Martin J B. Taphoorn [Pays-Bas] ; Corneel Coens [Belgique] ; Jacoline E C. Bromberg [Pays-Bas] ; Warren P. Mason [Canada] ; Khê Hoang-Xuan [France] ; Gail Ryan [Australie] ; Mohamed Ben Hassel [France] ; Roelien H. Enting [Pays-Bas] ; Alba A. Brandes [Italie] ; Antje Wick [Allemagne] ; Olivier Chinot [France] ; Michele Reni [Italie] ; Guy Kantor [France] ; Brian Thiessen [Canada] ; Martin Klein [Pays-Bas] ; Eugenie Verger [Espagne] ; Christian Borchers [Allemagne] ; Peter Hau [Allemagne] ; Michael Back [Australie] ; Anja Smits [Suède] ; Vassilis Golfinopoulos [Belgique] ; Thierry Gorlia [Belgique] ; Andrew Bottomley [Belgique] ; Roger Stupp [Suisse] ; Brigitta G. Baumert [Allemagne]Source :
- The Lancet. Oncology [ 1474-5488 ] ; 2016.
Descripteurs français
- KwdFr :
- Dacarbazine (analogues et dérivés), Dacarbazine (usage thérapeutique), Gliome (mortalité), Gliome (psychologie), Gliome (radiothérapie), Gliome (traitement médicamenteux), Grading des tumeurs, Humains, Qualité de vie, Tumeurs du cerveau (mortalité), Tumeurs du cerveau (psychologie), Tumeurs du cerveau (radiothérapie), Tumeurs du cerveau (traitement médicamenteux), Études prospectives.
- MESH :
- analogues et dérivés : Dacarbazine.
- mortalité : Gliome, Tumeurs du cerveau.
- psychologie : Gliome, Tumeurs du cerveau.
- radiothérapie : Gliome, Tumeurs du cerveau.
- traitement médicamenteux : Gliome, Tumeurs du cerveau.
- usage thérapeutique : Dacarbazine.
- Grading des tumeurs, Humains, Qualité de vie, Études prospectives.
English descriptors
- KwdEn :
- Brain Neoplasms (drug therapy), Brain Neoplasms (mortality), Brain Neoplasms (psychology), Brain Neoplasms (radiotherapy), Dacarbazine (analogs & derivatives), Dacarbazine (therapeutic use), Glioma (drug therapy), Glioma (mortality), Glioma (psychology), Glioma (radiotherapy), Humans, Neoplasm Grading, Prospective Studies, Quality of Life.
- MESH :
- chemical , analogs & derivatives : Dacarbazine.
- drug therapy : Brain Neoplasms, Glioma.
- mortality : Brain Neoplasms, Glioma.
- psychology : Brain Neoplasms, Glioma.
- radiotherapy : Brain Neoplasms, Glioma.
- chemical , therapeutic use : Dacarbazine.
- Humans, Neoplasm Grading, Prospective Studies, Quality of Life.
Abstract
Temozolomide chemotherapy versus radiotherapy in patients with a high-risk low-grade glioma has been shown to have no significant effect on progression-free survival. If these treatments have a different effect on health-related quality of life (HRQOL), it might affect the choice of therapy. We postulated that temozolomide compromises HRQOL and global cognitive functioning to a lesser extent than does radiotherapy.
DOI: 10.1016/S1470-2045(16)30305-9
PubMed: 27686943
Affiliations:
- Allemagne, Australie, Belgique, Canada, Espagne, France, Italie, Pays-Bas, Suisse, Suède
- Aquitaine, Bade-Wurtemberg, Canton de Vaud, Catalogne, District de Cologne, District de Karlsruhe, Groningue (province), Hollande-Méridionale, Hollande-Septentrionale, Lombardie, Nouvelle-Aquitaine, Ontario, Provence-Alpes-Côte d'Azur, Rhénanie-du-Nord-Westphalie, Région Bretagne, Région de Bruxelles-Capitale, Île-de-France
- Amsterdam, Barcelone, Bonn, Bordeaux, Bruxelles, Groningue, Groningue (ville), Heidelberg, Lausanne, Marseille, Milan, Paris, Rennes, Rotterdam, Toronto
- Université d'Aix-Marseille, Université de Groningue, Université de Toronto
Links toward previous steps (curation, corpus...)
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Le document en format XML
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Electronic address: jc.reijneveld@vumc.nl.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology, Brain Tumor Centre Amsterdam, VU University Medical Centre and Academic Medical Centre, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Taphoorn, Martin J B" sort="Taphoorn, Martin J B" uniqKey="Taphoorn M" first="Martin J B" last="Taphoorn">Martin J B. Taphoorn</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Medical Centre Haaglanden and Leiden University Medical Centre, The Hague, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology, Medical Centre Haaglanden and Leiden University Medical Centre, The Hague</wicri:regionArea><wicri:noRegion>The Hague</wicri:noRegion></affiliation></author><author><name sortKey="Coens, Corneel" sort="Coens, Corneel" uniqKey="Coens C" first="Corneel" last="Coens">Corneel Coens</name><affiliation wicri:level="3"><nlm:affiliation>Department of Quality of Life, European Organisation for Research and Treatment of Cancer Headquarters, Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Quality of Life, European Organisation for Research and Treatment of Cancer Headquarters, Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Bromberg, Jacoline E C" sort="Bromberg, Jacoline E C" uniqKey="Bromberg J" first="Jacoline E C" last="Bromberg">Jacoline E C. Bromberg</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neuro-oncology, Erasmus MC University MC Cancer Centre, Rotterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neuro-oncology, Erasmus MC University MC Cancer Centre, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Mason, Warren P" sort="Mason, Warren P" uniqKey="Mason W" first="Warren P" last="Mason">Warren P. Mason</name><affiliation wicri:level="4"><nlm:affiliation>Princess Margaret Hospital, University of Toronto, Toronto, ON, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Princess Margaret Hospital, University of Toronto, Toronto, ON</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Hoang Xuan, Khe" sort="Hoang Xuan, Khe" uniqKey="Hoang Xuan K" first="Khê" last="Hoang-Xuan">Khê Hoang-Xuan</name><affiliation wicri:level="3"><nlm:affiliation>APHP, Department of Neurology, Pitié-Salpêtrière Hospital, UPMC, Sorbonne Universités, IHU, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>APHP, Department of Neurology, Pitié-Salpêtrière Hospital, UPMC, Sorbonne Universités, IHU, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Ryan, Gail" sort="Ryan, Gail" uniqKey="Ryan G" first="Gail" last="Ryan">Gail Ryan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC</wicri:regionArea><wicri:noRegion>VIC</wicri:noRegion></affiliation></author><author><name sortKey="Hassel, Mohamed Ben" sort="Hassel, Mohamed Ben" uniqKey="Hassel M" first="Mohamed Ben" last="Hassel">Mohamed Ben Hassel</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medical Oncology and Department of Radiotherapy, Centre Eugène Marquis, Rennes, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Medical Oncology and Department of Radiotherapy, Centre Eugène Marquis, Rennes</wicri:regionArea><placeName><region type="region">Région Bretagne</region><region type="old region">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation></author><author><name sortKey="Enting, Roelien H" sort="Enting, Roelien H" uniqKey="Enting R" first="Roelien H" last="Enting">Roelien H. Enting</name><affiliation wicri:level="4"><nlm:affiliation>Department of Neurology, University of Groningen, University Medical Centre, Groningen, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology, University of Groningen, University Medical Centre, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region><settlement type="city">Groningue (ville)</settlement></placeName><orgName type="university">Université de Groningue</orgName></affiliation></author><author><name sortKey="Brandes, Alba A" sort="Brandes, Alba A" uniqKey="Brandes A" first="Alba A" last="Brandes">Alba A. Brandes</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Oncology, AUSL-IRCCS Scienze Neurologiche, Bologna, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Medical Oncology, AUSL-IRCCS Scienze Neurologiche, Bologna</wicri:regionArea><wicri:noRegion>Bologna</wicri:noRegion></affiliation></author><author><name sortKey="Wick, Antje" sort="Wick, Antje" uniqKey="Wick A" first="Antje" last="Wick">Antje Wick</name><affiliation wicri:level="3"><nlm:affiliation>Neurology Clinic, University of Heidelberg Medical Centre and NCT Neurooncology in DKTK of the German Cancer Research Center (DKFZ), Heidelberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Neurology Clinic, University of Heidelberg Medical Centre and NCT Neurooncology in DKTK of the German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Chinot, Olivier" sort="Chinot, Olivier" uniqKey="Chinot O" first="Olivier" last="Chinot">Olivier Chinot</name><affiliation wicri:level="4"><nlm:affiliation>Aix Marseille Universite, APHM, Hopital de La Timone, Department of Neuro-Oncology, Marseille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Aix Marseille Universite, APHM, Hopital de La Timone, Department of Neuro-Oncology, Marseille</wicri:regionArea><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement><settlement type="city">Marseille</settlement></placeName><orgName type="university">Université d'Aix-Marseille</orgName></affiliation></author><author><name sortKey="Reni, Michele" sort="Reni, Michele" uniqKey="Reni M" first="Michele" last="Reni">Michele Reni</name><affiliation wicri:level="3"><nlm:affiliation>IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>IRCCS San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Kantor, Guy" sort="Kantor, Guy" uniqKey="Kantor G" first="Guy" last="Kantor">Guy Kantor</name><affiliation wicri:level="3"><nlm:affiliation>Department of Radiotherapy, Institut Bergonié, Comprehensive Cancer Centre, Bordeaux, Bordeaux, France; Department of Radiotherapy, University Bordeaux Segalen, Bordeaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Radiotherapy, Institut Bergonié, Comprehensive Cancer Centre, Bordeaux, Bordeaux, France; Department of Radiotherapy, University Bordeaux Segalen, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Thiessen, Brian" sort="Thiessen, Brian" uniqKey="Thiessen B" first="Brian" last="Thiessen">Brian Thiessen</name><affiliation wicri:level="1"><nlm:affiliation>BC Cancer Agency, Vancouver, BC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>BC Cancer Agency, Vancouver, BC</wicri:regionArea><wicri:noRegion>BC</wicri:noRegion></affiliation></author><author><name sortKey="Klein, Martin" sort="Klein, Martin" uniqKey="Klein M" first="Martin" last="Klein">Martin Klein</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medical Psychology, Brain Tumor Centre Amsterdam, VU University Medical Centre and Academic Medical Centre, Amsterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Psychology, Brain Tumor Centre Amsterdam, VU University Medical Centre and Academic Medical Centre, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Verger, Eugenie" sort="Verger, Eugenie" uniqKey="Verger E" first="Eugenie" last="Verger">Eugenie Verger</name><affiliation wicri:level="3"><nlm:affiliation>Department of Radiation-Oncology, Hospital Clinic Universitari, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Radiation-Oncology, Hospital Clinic Universitari, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Borchers, Christian" sort="Borchers, Christian" uniqKey="Borchers C" first="Christian" last="Borchers">Christian Borchers</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, University Hospital Tübingen, Tübingen, Germany; Centre of Neuromedicine, North-West-Hospital Sanderbusch, Sande, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, University Hospital Tübingen, Tübingen, Germany; Centre of Neuromedicine, North-West-Hospital Sanderbusch, Sande</wicri:regionArea><wicri:noRegion>Sande</wicri:noRegion><wicri:noRegion>Sande</wicri:noRegion><wicri:noRegion>Sande</wicri:noRegion></affiliation></author><author><name sortKey="Hau, Peter" sort="Hau, Peter" uniqKey="Hau P" first="Peter" last="Hau">Peter Hau</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, University Hospital Regensburg, Regensburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, University Hospital Regensburg, Regensburg</wicri:regionArea><wicri:noRegion>Regensburg</wicri:noRegion><wicri:noRegion>Regensburg</wicri:noRegion><wicri:noRegion>Regensburg</wicri:noRegion></affiliation></author><author><name sortKey="Back, Michael" sort="Back, Michael" uniqKey="Back M" first="Michael" last="Back">Michael Back</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Royal North Shore Hospital, St Leonards, NSW, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Radiation Oncology, Royal North Shore Hospital, St Leonards, NSW</wicri:regionArea><wicri:noRegion>NSW</wicri:noRegion></affiliation></author><author><name sortKey="Smits, Anja" sort="Smits, Anja" uniqKey="Smits A" first="Anja" last="Smits">Anja Smits</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neuroscience, Neurology, Uppsala University and University Hospital, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neuroscience, Neurology, Uppsala University and University Hospital, Uppsala</wicri:regionArea><wicri:noRegion>Uppsala</wicri:noRegion></affiliation></author><author><name sortKey="Golfinopoulos, Vassilis" sort="Golfinopoulos, Vassilis" uniqKey="Golfinopoulos V" first="Vassilis" last="Golfinopoulos">Vassilis Golfinopoulos</name><affiliation wicri:level="3"><nlm:affiliation>Medical Department, European Organisation for Research and Treatment of Cancer Headquarters, Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Medical Department, European Organisation for Research and Treatment of Cancer Headquarters, Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Gorlia, Thierry" sort="Gorlia, Thierry" uniqKey="Gorlia T" first="Thierry" last="Gorlia">Thierry Gorlia</name><affiliation wicri:level="3"><nlm:affiliation>Department of Statistics, European Organisation for Research and Treatment of Cancer Headquarters, Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Statistics, European Organisation for Research and Treatment of Cancer Headquarters, Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Bottomley, Andrew" sort="Bottomley, Andrew" uniqKey="Bottomley A" first="Andrew" last="Bottomley">Andrew Bottomley</name><affiliation wicri:level="3"><nlm:affiliation>Department of Quality of Life, European Organisation for Research and Treatment of Cancer Headquarters, Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Quality of Life, European Organisation for Research and Treatment of Cancer Headquarters, Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Stupp, Roger" sort="Stupp, Roger" uniqKey="Stupp R" first="Roger" last="Stupp">Roger Stupp</name><affiliation wicri:level="3"><nlm:affiliation>Department of Clinical Neurosciences, Department of Neurosurgery, and Department of Oncology, University Hospital Lausanne, Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Clinical Neurosciences, Department of Neurosurgery, and Department of Oncology, University Hospital Lausanne, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation></author><author><name sortKey="Baumert, Brigitta G" sort="Baumert, Brigitta G" uniqKey="Baumert B" first="Brigitta G" last="Baumert">Brigitta G. Baumert</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medical Oncology and Cancer Centre, University Hospital Zurich, Zurich, Switzerland; Department of Radiation-Oncology (MAASTRO), Maastricht University Medical Centre (MUMC) and GROW (School for Oncology), Maastricht, Netherlands; Department of Radiation-Oncology, MediClin Robert-Janker-Clinic, Clinical Cooperation Unit Neuro-oncology, University Bonn Medical Centre, Bonn, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Medical Oncology and Cancer Centre, University Hospital Zurich, Zurich, Switzerland; Department of Radiation-Oncology (MAASTRO), Maastricht University Medical Centre (MUMC) and GROW (School for Oncology), Maastricht, Netherlands; Department of Radiation-Oncology, MediClin Robert-Janker-Clinic, Clinical Cooperation Unit Neuro-oncology, University Bonn Medical Centre, Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:27686943</idno><idno type="pmid">27686943</idno><idno type="doi">10.1016/S1470-2045(16)30305-9</idno><idno type="wicri:Area/PubMed/Corpus">001606</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001606</idno><idno type="wicri:Area/PubMed/Curation">001584</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001584</idno><idno type="wicri:Area/PubMed/Checkpoint">001584</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001584</idno><idno type="wicri:Area/Ncbi/Merge">003C34</idno><idno type="wicri:Area/Ncbi/Curation">003C34</idno><idno type="wicri:Area/Ncbi/Checkpoint">003C34</idno><idno type="wicri:Area/Main/Merge">001D72</idno><idno type="wicri:Area/Main/Curation">001D75</idno><idno type="wicri:Area/Main/Exploration">001D75</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Health-related quality of life in patients with high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study.</title><author><name sortKey="Reijneveld, Jaap C" sort="Reijneveld, Jaap C" uniqKey="Reijneveld J" first="Jaap C" last="Reijneveld">Jaap C. Reijneveld</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology, Brain Tumor Centre Amsterdam, VU University Medical Centre and Academic Medical Centre, Amsterdam, Netherlands. Electronic address: jc.reijneveld@vumc.nl.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology, Brain Tumor Centre Amsterdam, VU University Medical Centre and Academic Medical Centre, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Taphoorn, Martin J B" sort="Taphoorn, Martin J B" uniqKey="Taphoorn M" first="Martin J B" last="Taphoorn">Martin J B. Taphoorn</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Medical Centre Haaglanden and Leiden University Medical Centre, The Hague, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology, Medical Centre Haaglanden and Leiden University Medical Centre, The Hague</wicri:regionArea><wicri:noRegion>The Hague</wicri:noRegion></affiliation></author><author><name sortKey="Coens, Corneel" sort="Coens, Corneel" uniqKey="Coens C" first="Corneel" last="Coens">Corneel Coens</name><affiliation wicri:level="3"><nlm:affiliation>Department of Quality of Life, European Organisation for Research and Treatment of Cancer Headquarters, Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Quality of Life, European Organisation for Research and Treatment of Cancer Headquarters, Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Bromberg, Jacoline E C" sort="Bromberg, Jacoline E C" uniqKey="Bromberg J" first="Jacoline E C" last="Bromberg">Jacoline E C. Bromberg</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neuro-oncology, Erasmus MC University MC Cancer Centre, Rotterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neuro-oncology, Erasmus MC University MC Cancer Centre, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Mason, Warren P" sort="Mason, Warren P" uniqKey="Mason W" first="Warren P" last="Mason">Warren P. Mason</name><affiliation wicri:level="4"><nlm:affiliation>Princess Margaret Hospital, University of Toronto, Toronto, ON, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Princess Margaret Hospital, University of Toronto, Toronto, ON</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Hoang Xuan, Khe" sort="Hoang Xuan, Khe" uniqKey="Hoang Xuan K" first="Khê" last="Hoang-Xuan">Khê Hoang-Xuan</name><affiliation wicri:level="3"><nlm:affiliation>APHP, Department of Neurology, Pitié-Salpêtrière Hospital, UPMC, Sorbonne Universités, IHU, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>APHP, Department of Neurology, Pitié-Salpêtrière Hospital, UPMC, Sorbonne Universités, IHU, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Ryan, Gail" sort="Ryan, Gail" uniqKey="Ryan G" first="Gail" last="Ryan">Gail Ryan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC</wicri:regionArea><wicri:noRegion>VIC</wicri:noRegion></affiliation></author><author><name sortKey="Hassel, Mohamed Ben" sort="Hassel, Mohamed Ben" uniqKey="Hassel M" first="Mohamed Ben" last="Hassel">Mohamed Ben Hassel</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medical Oncology and Department of Radiotherapy, Centre Eugène Marquis, Rennes, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Medical Oncology and Department of Radiotherapy, Centre Eugène Marquis, Rennes</wicri:regionArea><placeName><region type="region">Région Bretagne</region><region type="old region">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation></author><author><name sortKey="Enting, Roelien H" sort="Enting, Roelien H" uniqKey="Enting R" first="Roelien H" last="Enting">Roelien H. Enting</name><affiliation wicri:level="4"><nlm:affiliation>Department of Neurology, University of Groningen, University Medical Centre, Groningen, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology, University of Groningen, University Medical Centre, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region><settlement type="city">Groningue (ville)</settlement></placeName><orgName type="university">Université de Groningue</orgName></affiliation></author><author><name sortKey="Brandes, Alba A" sort="Brandes, Alba A" uniqKey="Brandes A" first="Alba A" last="Brandes">Alba A. Brandes</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Oncology, AUSL-IRCCS Scienze Neurologiche, Bologna, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Medical Oncology, AUSL-IRCCS Scienze Neurologiche, Bologna</wicri:regionArea><wicri:noRegion>Bologna</wicri:noRegion></affiliation></author><author><name sortKey="Wick, Antje" sort="Wick, Antje" uniqKey="Wick A" first="Antje" last="Wick">Antje Wick</name><affiliation wicri:level="3"><nlm:affiliation>Neurology Clinic, University of Heidelberg Medical Centre and NCT Neurooncology in DKTK of the German Cancer Research Center (DKFZ), Heidelberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Neurology Clinic, University of Heidelberg Medical Centre and NCT Neurooncology in DKTK of the German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Chinot, Olivier" sort="Chinot, Olivier" uniqKey="Chinot O" first="Olivier" last="Chinot">Olivier Chinot</name><affiliation wicri:level="4"><nlm:affiliation>Aix Marseille Universite, APHM, Hopital de La Timone, Department of Neuro-Oncology, Marseille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Aix Marseille Universite, APHM, Hopital de La Timone, Department of Neuro-Oncology, Marseille</wicri:regionArea><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement><settlement type="city">Marseille</settlement></placeName><orgName type="university">Université d'Aix-Marseille</orgName></affiliation></author><author><name sortKey="Reni, Michele" sort="Reni, Michele" uniqKey="Reni M" first="Michele" last="Reni">Michele Reni</name><affiliation wicri:level="3"><nlm:affiliation>IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>IRCCS San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Kantor, Guy" sort="Kantor, Guy" uniqKey="Kantor G" first="Guy" last="Kantor">Guy Kantor</name><affiliation wicri:level="3"><nlm:affiliation>Department of Radiotherapy, Institut Bergonié, Comprehensive Cancer Centre, Bordeaux, Bordeaux, France; Department of Radiotherapy, University Bordeaux Segalen, Bordeaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Radiotherapy, Institut Bergonié, Comprehensive Cancer Centre, Bordeaux, Bordeaux, France; Department of Radiotherapy, University Bordeaux Segalen, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Thiessen, Brian" sort="Thiessen, Brian" uniqKey="Thiessen B" first="Brian" last="Thiessen">Brian Thiessen</name><affiliation wicri:level="1"><nlm:affiliation>BC Cancer Agency, Vancouver, BC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>BC Cancer Agency, Vancouver, BC</wicri:regionArea><wicri:noRegion>BC</wicri:noRegion></affiliation></author><author><name sortKey="Klein, Martin" sort="Klein, Martin" uniqKey="Klein M" first="Martin" last="Klein">Martin Klein</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medical Psychology, Brain Tumor Centre Amsterdam, VU University Medical Centre and Academic Medical Centre, Amsterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Psychology, Brain Tumor Centre Amsterdam, VU University Medical Centre and Academic Medical Centre, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Verger, Eugenie" sort="Verger, Eugenie" uniqKey="Verger E" first="Eugenie" last="Verger">Eugenie Verger</name><affiliation wicri:level="3"><nlm:affiliation>Department of Radiation-Oncology, Hospital Clinic Universitari, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Radiation-Oncology, Hospital Clinic Universitari, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Borchers, Christian" sort="Borchers, Christian" uniqKey="Borchers C" first="Christian" last="Borchers">Christian Borchers</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, University Hospital Tübingen, Tübingen, Germany; Centre of Neuromedicine, North-West-Hospital Sanderbusch, Sande, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, University Hospital Tübingen, Tübingen, Germany; Centre of Neuromedicine, North-West-Hospital Sanderbusch, Sande</wicri:regionArea><wicri:noRegion>Sande</wicri:noRegion><wicri:noRegion>Sande</wicri:noRegion><wicri:noRegion>Sande</wicri:noRegion></affiliation></author><author><name sortKey="Hau, Peter" sort="Hau, Peter" uniqKey="Hau P" first="Peter" last="Hau">Peter Hau</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, University Hospital Regensburg, Regensburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, University Hospital Regensburg, Regensburg</wicri:regionArea><wicri:noRegion>Regensburg</wicri:noRegion><wicri:noRegion>Regensburg</wicri:noRegion><wicri:noRegion>Regensburg</wicri:noRegion></affiliation></author><author><name sortKey="Back, Michael" sort="Back, Michael" uniqKey="Back M" first="Michael" last="Back">Michael Back</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Royal North Shore Hospital, St Leonards, NSW, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Radiation Oncology, Royal North Shore Hospital, St Leonards, NSW</wicri:regionArea><wicri:noRegion>NSW</wicri:noRegion></affiliation></author><author><name sortKey="Smits, Anja" sort="Smits, Anja" uniqKey="Smits A" first="Anja" last="Smits">Anja Smits</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neuroscience, Neurology, Uppsala University and University Hospital, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neuroscience, Neurology, Uppsala University and University Hospital, Uppsala</wicri:regionArea><wicri:noRegion>Uppsala</wicri:noRegion></affiliation></author><author><name sortKey="Golfinopoulos, Vassilis" sort="Golfinopoulos, Vassilis" uniqKey="Golfinopoulos V" first="Vassilis" last="Golfinopoulos">Vassilis Golfinopoulos</name><affiliation wicri:level="3"><nlm:affiliation>Medical Department, European Organisation for Research and Treatment of Cancer Headquarters, Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Medical Department, European Organisation for Research and Treatment of Cancer Headquarters, Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Gorlia, Thierry" sort="Gorlia, Thierry" uniqKey="Gorlia T" first="Thierry" last="Gorlia">Thierry Gorlia</name><affiliation wicri:level="3"><nlm:affiliation>Department of Statistics, European Organisation for Research and Treatment of Cancer Headquarters, Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Statistics, European Organisation for Research and Treatment of Cancer Headquarters, Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Bottomley, Andrew" sort="Bottomley, Andrew" uniqKey="Bottomley A" first="Andrew" last="Bottomley">Andrew Bottomley</name><affiliation wicri:level="3"><nlm:affiliation>Department of Quality of Life, European Organisation for Research and Treatment of Cancer Headquarters, Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Quality of Life, European Organisation for Research and Treatment of Cancer Headquarters, Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Stupp, Roger" sort="Stupp, Roger" uniqKey="Stupp R" first="Roger" last="Stupp">Roger Stupp</name><affiliation wicri:level="3"><nlm:affiliation>Department of Clinical Neurosciences, Department of Neurosurgery, and Department of Oncology, University Hospital Lausanne, Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Clinical Neurosciences, Department of Neurosurgery, and Department of Oncology, University Hospital Lausanne, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation></author><author><name sortKey="Baumert, Brigitta G" sort="Baumert, Brigitta G" uniqKey="Baumert B" first="Brigitta G" last="Baumert">Brigitta G. Baumert</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medical Oncology and Cancer Centre, University Hospital Zurich, Zurich, Switzerland; Department of Radiation-Oncology (MAASTRO), Maastricht University Medical Centre (MUMC) and GROW (School for Oncology), Maastricht, Netherlands; Department of Radiation-Oncology, MediClin Robert-Janker-Clinic, Clinical Cooperation Unit Neuro-oncology, University Bonn Medical Centre, Bonn, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Medical Oncology and Cancer Centre, University Hospital Zurich, Zurich, Switzerland; Department of Radiation-Oncology (MAASTRO), Maastricht University Medical Centre (MUMC) and GROW (School for Oncology), Maastricht, Netherlands; Department of Radiation-Oncology, MediClin Robert-Janker-Clinic, Clinical Cooperation Unit Neuro-oncology, University Bonn Medical Centre, Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation></author></analytic><series><title level="j">The Lancet. Oncology</title><idno type="eISSN">1474-5488</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Brain Neoplasms (drug therapy)</term><term>Brain Neoplasms (mortality)</term><term>Brain Neoplasms (psychology)</term><term>Brain Neoplasms (radiotherapy)</term><term>Dacarbazine (analogs & derivatives)</term><term>Dacarbazine (therapeutic use)</term><term>Glioma (drug therapy)</term><term>Glioma (mortality)</term><term>Glioma (psychology)</term><term>Glioma (radiotherapy)</term><term>Humans</term><term>Neoplasm Grading</term><term>Prospective Studies</term><term>Quality of Life</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Dacarbazine (analogues et dérivés)</term><term>Dacarbazine (usage thérapeutique)</term><term>Gliome (mortalité)</term><term>Gliome (psychologie)</term><term>Gliome (radiothérapie)</term><term>Gliome (traitement médicamenteux)</term><term>Grading des tumeurs</term><term>Humains</term><term>Qualité de vie</term><term>Tumeurs du cerveau (mortalité)</term><term>Tumeurs du cerveau (psychologie)</term><term>Tumeurs du cerveau (radiothérapie)</term><term>Tumeurs du cerveau (traitement médicamenteux)</term><term>Études prospectives</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en"><term>Dacarbazine</term></keywords><keywords scheme="MESH" qualifier="analogues et dérivés" xml:lang="fr"><term>Dacarbazine</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Brain Neoplasms</term><term>Glioma</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Brain Neoplasms</term><term>Glioma</term></keywords><keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Gliome</term><term>Tumeurs du cerveau</term></keywords><keywords scheme="MESH" qualifier="psychologie" xml:lang="fr"><term>Gliome</term><term>Tumeurs du cerveau</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Brain Neoplasms</term><term>Glioma</term></keywords><keywords scheme="MESH" qualifier="radiotherapy" xml:lang="en"><term>Brain Neoplasms</term><term>Glioma</term></keywords><keywords scheme="MESH" qualifier="radiothérapie" xml:lang="fr"><term>Gliome</term><term>Tumeurs du cerveau</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Dacarbazine</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Gliome</term><term>Tumeurs du cerveau</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Dacarbazine</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term><term>Neoplasm Grading</term><term>Prospective Studies</term><term>Quality of Life</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Grading des tumeurs</term><term>Humains</term><term>Qualité de vie</term><term>Études prospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Temozolomide chemotherapy versus radiotherapy in patients with a high-risk low-grade glioma has been shown to have no significant effect on progression-free survival. If these treatments have a different effect on health-related quality of life (HRQOL), it might affect the choice of therapy. We postulated that temozolomide compromises HRQOL and global cognitive functioning to a lesser extent than does radiotherapy.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Belgique</li><li>Canada</li><li>Espagne</li><li>France</li><li>Italie</li><li>Pays-Bas</li><li>Suisse</li><li>Suède</li></country><region><li>Aquitaine</li><li>Bade-Wurtemberg</li><li>Canton de Vaud</li><li>Catalogne</li><li>District de Cologne</li><li>District de Karlsruhe</li><li>Groningue (province)</li><li>Hollande-Méridionale</li><li>Hollande-Septentrionale</li><li>Lombardie</li><li>Nouvelle-Aquitaine</li><li>Ontario</li><li>Provence-Alpes-Côte d'Azur</li><li>Rhénanie-du-Nord-Westphalie</li><li>Région Bretagne</li><li>Région de Bruxelles-Capitale</li><li>Île-de-France</li></region><settlement><li>Amsterdam</li><li>Barcelone</li><li>Bonn</li><li>Bordeaux</li><li>Bruxelles</li><li>Groningue</li><li>Groningue (ville)</li><li>Heidelberg</li><li>Lausanne</li><li>Marseille</li><li>Milan</li><li>Paris</li><li>Rennes</li><li>Rotterdam</li><li>Toronto</li></settlement><orgName><li>Université d'Aix-Marseille</li><li>Université de Groningue</li><li>Université de Toronto</li></orgName></list><tree><country name="Pays-Bas"><region name="Hollande-Septentrionale"><name sortKey="Reijneveld, Jaap C" sort="Reijneveld, Jaap C" uniqKey="Reijneveld J" first="Jaap C" last="Reijneveld">Jaap C. Reijneveld</name></region><name sortKey="Bromberg, Jacoline E C" sort="Bromberg, Jacoline E C" uniqKey="Bromberg J" first="Jacoline E C" last="Bromberg">Jacoline E C. Bromberg</name><name sortKey="Enting, Roelien H" sort="Enting, Roelien H" uniqKey="Enting R" first="Roelien H" last="Enting">Roelien H. Enting</name><name sortKey="Klein, Martin" sort="Klein, Martin" uniqKey="Klein M" first="Martin" last="Klein">Martin Klein</name><name sortKey="Taphoorn, Martin J B" sort="Taphoorn, Martin J B" uniqKey="Taphoorn M" first="Martin J B" last="Taphoorn">Martin J B. Taphoorn</name></country><country name="Belgique"><region name="Région de Bruxelles-Capitale"><name sortKey="Coens, Corneel" sort="Coens, Corneel" uniqKey="Coens C" first="Corneel" last="Coens">Corneel Coens</name></region><name sortKey="Bottomley, Andrew" sort="Bottomley, Andrew" uniqKey="Bottomley A" first="Andrew" last="Bottomley">Andrew Bottomley</name><name sortKey="Golfinopoulos, Vassilis" sort="Golfinopoulos, Vassilis" uniqKey="Golfinopoulos V" first="Vassilis" last="Golfinopoulos">Vassilis Golfinopoulos</name><name sortKey="Gorlia, Thierry" sort="Gorlia, Thierry" uniqKey="Gorlia T" first="Thierry" last="Gorlia">Thierry Gorlia</name></country><country name="Canada"><region name="Ontario"><name sortKey="Mason, Warren P" sort="Mason, Warren P" uniqKey="Mason W" first="Warren P" last="Mason">Warren P. Mason</name></region><name sortKey="Thiessen, Brian" sort="Thiessen, Brian" uniqKey="Thiessen B" first="Brian" last="Thiessen">Brian Thiessen</name></country><country name="France"><region name="Île-de-France"><name sortKey="Hoang Xuan, Khe" sort="Hoang Xuan, Khe" uniqKey="Hoang Xuan K" first="Khê" last="Hoang-Xuan">Khê Hoang-Xuan</name></region><name sortKey="Chinot, Olivier" sort="Chinot, Olivier" uniqKey="Chinot O" first="Olivier" last="Chinot">Olivier Chinot</name><name sortKey="Hassel, Mohamed Ben" sort="Hassel, Mohamed Ben" uniqKey="Hassel M" first="Mohamed Ben" last="Hassel">Mohamed Ben Hassel</name><name sortKey="Kantor, Guy" sort="Kantor, Guy" uniqKey="Kantor G" first="Guy" last="Kantor">Guy Kantor</name></country><country name="Australie"><noRegion><name sortKey="Ryan, Gail" sort="Ryan, Gail" uniqKey="Ryan G" first="Gail" last="Ryan">Gail Ryan</name></noRegion><name sortKey="Back, Michael" sort="Back, Michael" uniqKey="Back M" first="Michael" last="Back">Michael Back</name></country><country name="Italie"><noRegion><name sortKey="Brandes, Alba A" sort="Brandes, Alba A" uniqKey="Brandes A" first="Alba A" last="Brandes">Alba A. Brandes</name></noRegion><name sortKey="Reni, Michele" sort="Reni, Michele" uniqKey="Reni M" first="Michele" last="Reni">Michele Reni</name></country><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Wick, Antje" sort="Wick, Antje" uniqKey="Wick A" first="Antje" last="Wick">Antje Wick</name></region><name sortKey="Baumert, Brigitta G" sort="Baumert, Brigitta G" uniqKey="Baumert B" first="Brigitta G" last="Baumert">Brigitta G. Baumert</name><name sortKey="Borchers, Christian" sort="Borchers, Christian" uniqKey="Borchers C" first="Christian" last="Borchers">Christian Borchers</name><name sortKey="Hau, Peter" sort="Hau, Peter" uniqKey="Hau P" first="Peter" last="Hau">Peter Hau</name></country><country name="Espagne"><region name="Catalogne"><name sortKey="Verger, Eugenie" sort="Verger, Eugenie" uniqKey="Verger E" first="Eugenie" last="Verger">Eugenie Verger</name></region></country><country name="Suède"><noRegion><name sortKey="Smits, Anja" sort="Smits, Anja" uniqKey="Smits A" first="Anja" last="Smits">Anja Smits</name></noRegion></country><country name="Suisse"><region name="Canton de Vaud"><name sortKey="Stupp, Roger" sort="Stupp, Roger" uniqKey="Stupp R" first="Roger" last="Stupp">Roger Stupp</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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